mRNA: changes the way we treat diseases from the flu to cancer

- Discovery-Dr. Vihari shadow

- Messenger RNA vaccines teach our cells how to make proteins to trigger the immune system in our body

In recent years, an epidemic called SARS has spread around the world. Bird flu then spread fear everywhere. Currently, a widespread epidemic called Kovid 12 has swept the world. The virus continues to attack with its new nature.

This virus may be our enemy, but it teaches us one or two things. When a virus enters our body, it hijacks our cells and uses them to make more virulent material. It enters our bodies with a demonic strategy of rapidly increasing their forces and attacking our immune system. The point is, if they can order our cellular protein factories to carry out their own purposes, why can't we strengthen our defenses? We can. " They tell our cells to produce proteins using the genetic material, Messenger RNA, which teaches our bodies to recognize and even fight off invaders.

This research could revolutionize the treatment of many types of conditions - and make individual therapy cheaper and easier. Prior to the Kovid-12 epidemic, the technology was viewed with suspicion, but confidence in its use is growing.

Now the question is, what is this RNA? What is mRNA in this too?

We know that the unit of life is the cell. In English it is called cell. Organisms like bacteria are made up of only one cell. While human-like creatures are made up of many cells. Thus organisms can be unicellular and even multicellular. Even though bacteria are made up of a single cell, an adult is made up of 30,000 billion cells. But the cell is the unit of everyone's life. Can't be seen with the naked eye even with such a microscope. But it is not rude. Each cell is a chemical factory that is an extremely complex and narrow factory. This factory makes proteins, which are responsible for the growth and development of the body. Our body cells make hundreds of thousands of types of proteins. The structure of the cell can be divided into three main sections. (1) The nucleus of a cell is nucleus (2) cytoplasm and (3) cell membrane. In the nucleus of a cell is a molecule in the shape of a curved ladder called DNA for short. This atom is the blueprint for the life of an organism. Organisms, whether bacteria or humans, grow and develop according to the blueprint. Remember that the growth and development of an organism is the growth and development of its cells. Is the 'masonry' of the living cell. Now the question is what are cells made of? Cells are made up of thousands of types of proteins. So the second question is where and how proteins are made? So the protein is made in the cell itself. And what kind of protein to make is in the 'blue print' in the DNA of the living cell.

Now the cell also has other types of atoms. This is called RNA. One type of RNA is mRNA. It means messenger or messenger. His work according to its meaning. The blueprint in DNA signals the protein to the ribosome. The function of the ribosome is to synthesize proteins. That is to make protein. These proteins are made up of 20 types of amino acids. Each amino acid has its own structure. This structure consists of three-dimensional molecules of amino acids. So apparently making 20 types of proteins is in the 'blue print' in the DNA of the living cell.

Now the question is where do the ribosomes get the amino acid molecules from. For this purpose, the molecule called TRNA is in the cell. T stands for transfer. Its job is to pull the amino acid molecules from the cell juice to the ribosome. Remember that the cell structure is very narrow. It has many components. Among them DNA, MRNA, TRNA, ribosome synthesize proteins formed by a chain of amino acids.

The ribosome messenger actually binds to RNA and uses it as a sample to understand the proper sequence of amino acids in each protein molecule. Thus, its function is important in protein synthesis.

The ribosome is actually present in every human cell, from bacteria. No living thing can survive without it. Therefore, the ribosomes in the body's cells must be targeted to kill germs such as bacteria and viruses.

Messenger RNA (mRNA) vaccines teach our cells how to make proteins that trigger the immune response in our body. MRNA vaccines use laboratory-made mRNA to teach our cells how to make proteins. The protein that stimulates the immune response within our body. This immune response produces antibodies. If the virus actually enters our body, it can protect us from infection.

Vaccines are just the beginning. If we can enable our bodies to make drugs in this way, it opens the door to treat diseases ranging from bacterial infections to autoimmune conditions, rare genetic disorders and even cancer. It is a revolution in medicine. It is still early days but promising results are being obtained.