Vaccine experts: Louis Pasteur and Jonas Soc

Louis Pasteur: Rabies

Edward died in his hometown of 18, the year before Louis Pasteur was born in France, about a thousand kilometers south. Louis did important work in advancing vaccine research. Originally, Louis was a fan of art and wanted to pursue it, but circumstances led him to turn to science.

Louis has unfurled many flags in the world of science, two of which are the most significant. In order to preserve a milk for a long time, pasteurization was invented. That is why the whole world can use the milk made in dairy a few days ago by keeping it in the fridge at home.

Louis also told the world that germs play an important role in the fermentation process. At that time the French silk industry was in trouble. This is because the worm from which the silk was made got some disease. Louis studied it, and it was during this time that he became interested in zoology.

Another thing Louis did was find a vaccine, a rabies vaccine. The bullet-shaped rabies virus enters the dog's brain and turns it into a brain. The dog then assumes a very aggressive nature and bites anyone it encounters. The dog dies, and the one who bites also dies. In those days (and still are) when a rabid dog bites, there is usually no way out except death. The treatment I received was even more brutal.

This is because the area around the rabid dog bite is dammed. That is, the iron rod was burned and stuck in the skin. The 'treatment' hurts but so does the observer. Louis himself saw the condition, which is why he developed a rabies vaccine when he advanced in scientific research. Initially, Louis developed the vaccine only for dogs, and by the time he was 12, he had experimented with dogs and succeeded. But they were more afraid of using the vaccine on humans.

Coincidentally, in the second year, he got a chance in 19th. A nine-year-old boy named Joseph was bitten by a rabid dog. The dogs also gave birth to 12 children, not two or five. Louis found out, so he worked with Dr. Grancher to treat the baby. A total of 17 injections were given in ten days, including the drug Louis discovered. A few days later the result came and Louie's search was successful. Joseph recovered and never saw the effects of rabies again.

It also became the first case in the world when rabies was successfully treated with medicine instead of dams or other remedies. That same year, a 17-year-old boy who had been bitten by a dog approached Louis and was shown to have been cured. It became widely known, as Louis was already well-known as a vaccine specialist. Word of the rabies vaccine reached as far as the United States, and some even traveled across the Atlantic to France to be vaccinated.

For further research, Louis XIII opened the laboratory, which is now known as the Pasteur Institute.

An epidemic of anthrax was reported in the United States after the 2001 terrorist attacks. Someone comes there with an envelope and when he opens it, powder comes out of it. There was talk that the powder was anthrax and that the terrorists were spreading anthrax through the powder. Many of these envelopes actually contained the anthrax virus. But thanks to Louis, he also discovered the anthrax vaccine at the same time as the rabies. But anthrax was not as widespread as rabies, so it did not get as much publicity as it should. Louis had already discovered medicine for anthrax, cholera in chickens, etc. Then finally find the cure for rabies.

Personally, Louis was very sad. Three of their children died of the disease. One son was seriously wounded in the German-French war of 181. Even then, the German government did not help, so Louis hated the government. Louis rejected the German government's award of the medal years later out of hatred.

The rabies due to the vaccine has reached a very small number. Developed countries even vaccinate their dogs against rabies. Even so, rabies continues to cause death worldwide. Due to lack of awareness or some other reason, some classes in some countries still do not or cannot get this vaccine.

After a rabid dog bite, he had to take 14 injections around Dunty for treatment and now he has to take only five. But that is the cure for rabies. The only way to prevent it is to get vaccinated.

The term vaccination was not so popular at the time, researchers called it the Pasteur Treatment. But Pasteur said that everything that happened was due to the great researcher Edward Jenner. If he had not found the first vaccine, I would not have been able to advance in this vaccine science. This is why such treatment is now widely known as vaccination.

Jonas Sock: Polio

Polio (full name: poliomyelitis) was rampant in the United States during the 120's. In the 19th year, 4,000 cases were reported in the United States and 4,000 deaths were reported. We all know what happens in polio. US President Franklin Roosevelt also contracted polio as a child and lost some of his body parts. But in the early decades of the twentieth century, even a country like America was suffering from polio. Born in 1918, Jonas saw the plight of the United States. While studying in 190, Jonas began to take an interest in the science of vaccination. Jonas also took part in what became known as the flu vaccine during World War II.

At the age of 18, Jonas became the head of the University of Pittsburgh's laboratory, and the government provided him with a large amount of funds to develop a polio vaccine. Sock's work was not as difficult as that of Edward Jenner or Louis. The basic principles of vaccine discovery were already known. So now the only thing that had to be done was to identify the virus, do its part, and make a medicine that could attack the weak part.

Jonas did the work, experimenting on a polio patient, experimenting on himself and even vaccinating his family. All the results were positive, so on March 8, 19, Jonas announced on the radio that the polio vaccine was ready. Jonas did not take out his patent in the public interest. So when Jonas was asked in the 19th who has the patent for this drug, Jonas replied, to the public!

After various tests, the vaccine was found to be safe, so school children were vaccinated all over the United States. In the meantime, there was a case where two children were paralyzed and 10 died due to defective vaccination. Vaccine production was halted for some time, but annual polio cases in the United States dropped to 3,000.

The vaccine Jonas found was to be given by injection. It's straightforward that kids don't like injections. So Albert Sebin, a Polish-American researcher, discovered the drops of polio, which were like mouthwash. Since then, polio vaccination has become much easier and has spread around the world.

The world today is not completely polio free, with sporadic cases reported because some countries do not provide vaccines. Polio vaccination is also difficult in some parts of Pakistan-Afghanistan, which is ruled by terrorist organizations. But despite all these conditions, most of the earth today is polio-free. India has yet to be declared polio-free in 2017. So now it is unlikely that new cases will be registered.

Many epidemics came to the earth and then the vaccine was discovered. Some epidemics, such as the coronavirus, have come to a head, which has made scientists sweat to find a vaccine. But today vaccines for measles, chicken pox, tuberculosis, influenza, rotavirus, hepatitis, etc., have been developed and used worldwide. Vaccination has led to a number of epidemics in the last half-century.

Louis Pasteur (19-19)

Jonas Sock (1916-19)

What's in a vaccine?

Inactive viruses-bacteria contained in it

The answer is viruses or bacteria! A vaccine that is given to protect against a virus or bacteria is a medicine made from a virus or bacteria. But the virus-bacteria are inactivated. Cannot penetrate and sabotage the body, remain a fighter. It's as if the virus-bacteria have changed the heart! Apart from this, various elements are mixed in the vaccine as per the need of the disease.

Empire raging epidemic

One of the reasons for the fall of the Roman Empire was the then spreading plague. Smallpox destroyed the Inca and modern day cultures. Call it plague or smallpox or whatever. Turning the pages of history proves that epidemics have been the cause of the downfall of skinny emperors and cultures.

Many epidemics have been reported that have not destroyed the entire culture and have resulted in a large number of deaths. The last deadly epidemic was the Spanish flu (also spread from China) during 1917-20, which killed tens of millions of people.

How does the vaccine work?

There are many countries, including Italy and America, where childhood immunization is not practiced. Some vaccines are limited enough. He has taken dozens of vaccines wherever the child grows up. The value of a drop that looks like a drop of water may not be understood then but is now being understood by the world at the time of Corona.

This is because mortality has become uncontrollable only in countries where vaccination is not practiced. Researchers in the United States have reported that corona outbreaks have spread to countries where BCG vaccines are not available. On the other hand, there are some countries where a certificate has to be submitted that the child has been vaccinated before entering the school.

The vaccine is rag-covered rattan. The vaccine that enters the body does not have to do its duty every day, in fact some vaccines are not used once in a lifetime. But most of the time the vaccine stays dormant in the body. The vaccine is activated when a virus or bacterial disease is applied to the body. The job of this vaccine is to wake up a fighter called an antibody that is already in the body.

The vaccine awakens the fighters and sends them out to fight the invading virus. Then there is the fight between the body's immune system (antibodies) and viruses or bacteria. The work of vaccination is very simple, very important.

The World Health Organization wrote on its site, "If we stop vaccination, the diseases that have become extinct from the earth will rise again."